He is currently Chief Technology Officer at Q-State Biosciences working to advance Q-State technologies in drug discovery efforts. Homogenous scratch wounds were introduced using WoundMaker (Essen Bioscience, UK) and cells immediately stimulated with thrombin (10 nM). At both Essen and Merck, he worked on development of novel instrumentation and technologies to support drug discovery, which have led to several marketed products. The system provides insight into active biological processes in real-time which is not possible using single. He also worked as Director, Ion Channel Screening and Drug Discovery at Essen Bioscience, a leading instrument development company. A live-cell imaging and analysis platform that enables quantification of cell behavior over time (from hours to weeks) by automatically gathering and analyzing images around the clock, all within your incubator. Sartorius has agreed buy cell-based assay and instrumentation firm Essen BioScience from its private equity owner SFW. He was also Director of Operations at the Johns Hopkins Ion Channel Center, which provided HTS screening and lead optimization for ion channel and transporter targets for the academic community through the NIH Molecular Libraries program. Sartorius to Buy Essen for 320M to Acquire Live-Cell Imaging Platform. These teams produced a number of clinical candidate compounds in multiple therapeutic areas. 13, 2012 /PRNewswire/ - Essen BioScience Inc., a global provider of life science research tools and services, is announcing the first shipments of its new live cell imaging system, IncuCyte ZOOM, an expanded line of labeling reagents as well as a new kinetic neuronal imaging assay. He worked for over twenty years at Merck Research labs where he led basic research teams at multiple discovery stages including target identification and validation, assay development, lead identification and optimization. IncuCyte live-cell imaging systems, designed by Essen BioScience is the first instrument to provide automated real-time image capture and data analysis from hours to weeks, directly inside your. Owen McManus, Ph.D., is a drug discovery scientist with extensive experience in drug discovery, electrophysiology, and technology development.